Placental Site Nodule (PSN): An Uncommon Diagnosis with a Common Presentation

Placental site nodule is an uncommon, benign, generally asymptomatic lesion of trophoblastic origin, which may often be detected several months to years after the tenancy from which it resulted. PSN usually presents as menorrhagia, intermenstrual bleeding or an abnormal pap smear. PSN is benign, but it is important to distinguish it from the other benign and malignant lesions like decidua, placental polyp, exaggerated placental site and placental site trophoblastic tumor and squamous cell carcinoma. Follow ups of typical PSNs do not show recurrence or malignant potential.

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